Several states and a string of cautious local leaders won't change their mask mandates following the Centers for Disease Control and Prevention's new guidance.

Houston police were still searching on Saturday for a tiger that scared locals when it was seen briefly lurking around a suburban neighborhood last weekend.

DETROIT (AP) — Timothy Tharp has owned businesses in Detroit long enough to remember when parts of downtown resembled a ghost town. He’s also seen its resurgence with new restaurants, hotels and throngs of people since the city's emergence from bankruptcy....

Average weekly cases fell or were even in all U.S. states and territories except Wyoming, according to the latest data from the U.S. Centers for Disease Control and Prevention.

Audrey Nicole Francisquini was charged for entering American Senior High School giving out fliers to promote her Instagram account, reports say.

Americans have long been expected to provide proof of vaccination in some circumstances. COVID-19 vaccines won't be any different, experts say.