Visceral fat loss leaves 10-year 'metabolic legacy,' cutting diabetes risk by 28% despite weight regain
Medical Xpress
Last updated: June 15, 2026
Lifestyle interventions leading to a reduction in visceral fat, even if weight is regained, can offer lasting health benefits. This reduction in harmful abdominal fat is associated with improved cardiometabolic health and a decreased risk of type 2 diabetes.
- The study, involving 366 participants followed for a decade, found that despite participants returning to their baseline body weight, their waist circumference and abdominal fat depots remained lower.
- Crucially, each 10% reduction in visceral fat during an intervention correlated with a 30% lower risk of developing type 2 diabetes long-term.
- These benefits persisted even when accounting for factors like weight change, diet adherence, and physical activity.
- Visceral fat reduction, rather than overall weight loss, appears to be a key target for sustained cardiometabolic health and a reduced future risk of type 2 diabetes.
- The research highlights that not all weight loss is equivalent, with visceral fat loss demonstrating a more durable impact on metabolic well-being.
- The study utilized advanced MRI technology to precisely map internal fat depots, moving beyond BMI to understand the mobilization of these "hidden" fat stores.